Format: purified - Reactivity: human, rat, mouse, chicken - Synonym: Ptyr
Articlecode: PP2221
Clone:
Isotype: Rabbit polyclonal
Applications: WB, ELISA
WB: 1:1000 ELISA: 1:2000 IP: IC:
Synonym: Ptyr
BACKGROUND:
Phosphorylation of specific tyrosine residues is an important post-translational modification for regulating the activity of most proteins. Stimulation of a variety of cell signaling pathways activates the receptor and non-receptor tyrosine kinases that mediate these protein modifications. Antibodies that can detect phosphotyrosine residues are excellent tools for characterizing changes in the post-translational state of a broad range of phosphotyrosine-containing proteins. Immunoprecipitation of proteins of interest followed by detection of phosphotyrosine using anti-phosphotyrosine antibody is commonly used to correlate changes in tyrosine phosphorylation state with alterations in protein activity.
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