Reactivity: human, rat, chicken
Articlecode: 03-61098
Product: Anti-RAP/Pleo-Lipoprotein Receptor
Catalog #: 03-61098
Amount: 50 ml
CATEGORY: Rabbit Polyclonal
FORM: Serum containing 0.1% sodium azide
IMMUNOGEN: Recombinant human RAP (receptor-associated protein)
DESCRIPTION/SPECIFICITY: The antibody binds to an epitope of the C-terminal part of RAP, a sequence common to the human VLDL receptor superfamily (glycoprotein 330 and LRP), the chicken
oocyte receptor for VLDL and vitellogenin (LR8), and glycoprotein 330/megalin from rat.
No reaction with LDL receptor.
The antibody interferes with binding of VLDL and vitellogenin receptor. Binding is Ca2+-dependent with LR8.
ANTIGEN RECOGNIZED IN SPECIES (tested so far): Human: RAP, CD91 (LRP), VLDL-R
Chicken: LR8
Rat: gp330
RECOMMENDED FOR POSITIVE CONTROL: Formalin-fixed paraffin sections of cat Illeum
APPLICATION: Immunohistochemistry, suitable for frozen and paraffin sections
Ligand blotting
Western blotting
WORKING DILUTION: 1:50 to 1:100
DILUTION BUFFER: PBS with 0.5% BSA and 0.1% Na-Azide
STORAGE: 2-8°C for immediate use, or at -20°C (aliquot)
REFERENCES:
Hiesberger, T. et al. (1996) J. Biol. Chem. 271: 28792-28797
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