Reactivity: Human
Articlecode: 12--4238
Product: Secretin, human
Catalog #: 12-4238
Amount: 500 ìg
DESCRIPTION: Human Secretin stimulates the secretion of bicarbonate by the pancreas and inhibits the production of gastrin and acid production in the stomach. It also potentiates the release of digestive enzymes from the pancreas triggered by cholecystokinin. Secretin has a molecular formula of C130H220N44O40 ,a.a. sequence of -His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg- Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 and having a Mw of 3039.45.
SOURCE: Synthetic peptide
PURITY: > 98%, as determined by:
(a) Analysis by RP-HPLC and anion-exchange FPLC
(b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel
ENDOTOXIN: < 0.1 ng/µg (IEU/µg) of human Secretin
DIMERS & AGGREGATES: < 1% as determined by silver stained SDS-PAGE gel analysis
PROTEIN CONTENT: Protein quantitation was carried out by 2 independent methods:
- UV spectroscopy at 280 nm
- Analysis by RP-HPLC, using a standard solution of human Secretin as a Reference Standard
APPLICATION: Diagnosis of pancreatic dysfunction
Diagnosis of the presence of a gastrinoma
Autism - not yet approved applications
FORM: Purified, in 0.1 % BSA
STORAGE: -20°C (aliquot), avoid freezing and thawing cycles
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