Reactivity:
Articlecode: 12--4240
Product: Sincalide
Catalog #: 12-4240
Amount: 500 ìg
DESCRIPTION: Sincalide also called CCK-8 has a molecular formula of C49H62N10O16S3 , H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met- Asp- Phe- NH2 having a Mw of 1143.29
Sincalide corresponds to the C-terminal octapeptide of cholecystokinin (CCK) which acts on receptors within the gallbladder wall causing it to contract.
Cholecystokinin (CCK) is a hormone originally isolated from porcine intestinal mucosa and described as a linear 33-amino acid peptide containing a sulfated tyrosine, which is essential for its biological activity. It has been found in mammals in both the digestive tract and the central nervous system. Among its multiple biological functions, this hormone stimulates pancreatic exocrine secretion, gallbladder contraction, and intestine motility and may also act as a neurotransmitter/neuromodulator in the central nervous system
SOURCE: Synthetic peptide
PURITY: > 98%, as determined by:
(a) Analysis by RP-HPLC,
(b) Mass Spectral Anaylsis {MALDI-TOF exhibits correct Mw}.
FORM: Purified, in 0.1 % BSA
STORAGE: -20°C (aliquot), avoid freezing and thawing cycles
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