14-3-3-pan Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a protein belonging to the 14-3-3 family of proteins| members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases| suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants| which encode the same protein| have been identified for this gene.

Research Area: Neuroscience, Signal transduction, Stem cells, Cell biology

Synonyms: 14-3-3-pan, 14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, KCIP-1, 14-3-3 protein beta/alpha, N-terminally processed,

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year