3BP2 Polyclonal Antibody

Background:
SH3 domain binding protein 2(SH3BP2) Homo sapiens The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Immunogen: Synthesized peptide derived from human protein . at AA range: 210-290

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 61

GeneID: SH3BP2 3BP2 RES4-23

Storage: -20°C/1 year

NOTE: For Research Use Only