3MG polyclonal antibody, anti-human, mouse, rat

Background:
alternative products:Experimental confirmation may be lacking for some isoforms|Catalytic activity:Hydrolysis of alkylated DNA| releasing 3-methyladenine| 3-methylguanine| 7-methylguanine and 7-methyladenine.|Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine| and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.|Belongs to the DNA glycosylase MPG family.|subunit:Binds MBD1.|

Research Area: Epigenetics and nuclear signaling

Synonyms: DNA-3-methyladenine glycosylase (EC 3.2.2.21, 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, ADPG, N-methylpurine-DNA glycosylase)

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year