5HT2B Receptor polyclonal, anti-human, rat

Quantity: 100 µg

Background:
5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

Description:
Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 2B (HTR2B) detection. Tested with WB in Human, Rat.

Synonyms:
5 HT 2B antibody, 5 HT 2B receptor antibody, 5 HT(2B) antibody, 5 HT2B antibody, 5 hydroxytryptamine (serotonin) receptor 2B antibody, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody, 5 hydroxytryptamine 2B receptor antibody, 5 hydroxytryptamine receptor 2B antibody, 5-HT-2B antibody, 5-HT2B antibody, 5-hydroxytryptamine receptor 2B antibody, 5HT(2B) antibody, 5HT2B_HUMAN antibody, 5HT2F antibody, Htr 2b antibody, Htr2b antibody, NP75 protein antibody, SEROTONIN 5HT2B RECEPTOR antibody, Serotonin receptor 2B antibody, Stomach fundus serotonin receptor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor (446-478aa MRLRSSTIQSSSIILLDTLLLTENEGDKTEEQ V), different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor (446-478aa MRLRSSTIQSSSIILLDTLLLTENEGDKTEEQ V), different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.