5HT3A receptor polyclonal, anti-human

Quantity: 100 µg

Background:
HTR3A(5-HYDROXYTRYPTAMINE RECEPTOR 3A), also called SEROTONIN 5-HT-3 RECEPTOR, is a member of the ligand-gated ion channel receptor superfamily. HTR3A is a neurotransmitter in the central and peripheral nervous systems that plays a role in many physiologic processes such as sleep, appetite, thermoregulation, pain perception, hormone secretion, and sexual behavior. Using fluorescence in situ hybridization, the HTR3 gene is assigned to 11q23.1-q23.2. The single-channel conductance for homomers of HTR3A is 0.4 pS. Replacement of 3 arginine residues unique to the HA-stretch of the HTR3A subunit by their HTR3B subunit counterparts increases single-channel conductance 28-fold. Ultrastructural studies of the Torpedo nicotinic acetylcholine receptor indicated that the key residues might frame narrow openings that contribute to the permeation pathway. The genomic structure of the HTR3A gene contains 7 exons and spans approximately 14.5 kb.

Description:
Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 3A (HTR3A) detection. Tested with WB, IHC-P in Human.

Synonyms:
5 HT 3 antibody, 5 HT3 receptor antibody, 5 HT3A antibody, 5 HT3A receptor antibody, 5 HT3R antibody, 5 HT3RA antibody, 5 hydroxytryptamine(serotonin) receptor 3A antibody, 5-HT-3 antibody, 5-HT3-A antibody, 5-HT3A antibody, 5-HT3R antibody, 5-hydroxytryptamine receptor 3 antibody, 5-hydroxytryptamine receptor 3A antibody, 5HT 3 antibody, 5HT 3A antibody, 5HT receptor antibody, 5HT3 serotonin receptor antibody, 5HT3A_HUMAN antibody, 5HT3R antibody, HTR3 antibody, Htr3a antibody, Serotonin gated ion channel receptor antibody, Serotonin receptor 3A antibody, Serotonin-gated ion channel receptor 3a antibody, Serotonin-gated ion channel receptor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human5HT3A receptor(140-154aa RHQGEVQNYKPLQVV).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.