EIF3D polyclonal, anti-human

EIF3D polyclonal, anti-human

€470.00
In stock
SKU
AC-AP53345
Catalog Number: AC-AP55282
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P, IHC-F, IF, ICC, E
Datasheet
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Background:
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Antigen Type: A synthesized peptide

Antigen Type: EIF3D {ECO:0000255|HAMAP-Rule:MF_03003}
Gene ID: 8664
Primary Accession: O15371
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