7B2 polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins| including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function.

Research Area: Neuroscience, Signal transduction

Synonyms: Neuroendocrine protein 7B2 (Pituitary polypeptide, Secretogranin V, Secretogranin-5, Secretory granule endocrine protein I) [Cleaved into: N-terminal peptide, C-terminal peptide]

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year