α-Actin (Cardiac actin) (clone M8), anti-human, mouse, rat
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In stock
SKU
BMA1002
Catalog Number: BMA1002
Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, mouse, rat
Application(s): WB
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Size: 100 μg
Isotype: Mouse IgG1
Reactivity: human, mouse, rat
Application(s): WB
Request Information
Background:
Actin, alpha, skeletal muscle 1 (ACTA1) gene encodes skeletal muscle alpha-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction.1Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. 2Alpha-skeletal actin can activate a regulatory pathway linking a subset of muscle genes that operates independently of normal differentiation and withdrawal from the cell cycle.3
Immunogen:
A synthetic peptide (conjugated to KLH) corresponding to the N-terminal residues ofα-Actin.
Recommended Application:
Western Blot, WB(1:1000-2000)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
Actin, alpha, skeletal muscle 1 (ACTA1) gene encodes skeletal muscle alpha-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction.1Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. 2Alpha-skeletal actin can activate a regulatory pathway linking a subset of muscle genes that operates independently of normal differentiation and withdrawal from the cell cycle.3
Immunogen:
A synthetic peptide (conjugated to KLH) corresponding to the N-terminal residues ofα-Actin.
Recommended Application:
Western Blot, WB(1:1000-2000)
Product Form: Liquid
Purification: Protein A purified
Storage Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol and 0.05% Sodium Azide.
Storage Instruction:
Store at 4℃ after thawing (1 week). Aliquot and store at -20℃ for long term (at least one year). Avoid repeated freeze and thaw cycles.
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