A2M polyclonal, anti-human

Background:
This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Synonyms: Alpha-2-M；A2M, A2MD, alpha 2 Macroglobulin, FWP007,

Cellular Location: Secreted

Immunogen:
A synthetic peptide of human A2M

Gene Symbol: A2M

Gene ID: 2

Swiss prot: P01023

Calculated MW: 163kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.