AAK1 polyclonal, anti-human

Background:
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Other Names:
AP2-associated protein kinase 1, 2.7.11.1, Adaptor-associated kinase 1, AAK1, KIAA1048

Antigen Types:
Synthetic Peptide

Gene Name:
AAK1
Gene ID:
22848
Primary Accession: Q2M2I8
Other Accession: NP_055726;22848;269774 (mouse); 500244 (rat);