AAK1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP7861B
Catalog Number: AC-AP7861B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16779
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16779
Applications: WB
Datasheet
Request Information
Background:
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
Other Names:
AP2-associated protein kinase 1, Adaptor-associated kinase 1, AAK1, KIAA1048
Target/Specificity:
This AAK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 790-819 amino acids from the C-terminal region of human AAK1.
Antigen Region:
790-819
Antigen Type: Synthetic Peptide
Gene Name: AAK1
Gene ID: 22848
Primary Accession: Q2M2I8
NCBI Accession: NP_055726.3
Other Accession: P0C1X8; F1SPM8; Q3UHJ0; F1MH24
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
Other Names:
AP2-associated protein kinase 1, Adaptor-associated kinase 1, AAK1, KIAA1048
Target/Specificity:
This AAK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 790-819 amino acids from the C-terminal region of human AAK1.
Antigen Region:
790-819
Antigen Type: Synthetic Peptide
Gene Name: AAK1
Gene ID: 22848
Primary Accession: Q2M2I8
NCBI Accession: NP_055726.3
Other Accession: P0C1X8; F1SPM8; Q3UHJ0; F1MH24
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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