AAT1 polyclonal antibody, anti-human, mouse, rat

Background:
alternative products:Additional isoforms (AAT-1L and AAT-1S) may exist|Isoform 4 may play a role in spermatogenesis.|PTM:Isoform 4 is phosphorylated by PKA.|subcellular location:Isoform 4 is found in the mitochondria and localized in the neck of the sperm.|subunit:Interacts with AMY1 and AKAP1. Isoform 4 belongs to a complex together with AMY1| AKAP1 and PRKAR2B. Isoform 3 does not interact with AMY1.|tissue specificity:Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed| but strongly expressed in all spermatogenesis-related tissues| including the testis| the epithelium of cauda and the corpus epididymis. Isoform 4 is present in the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the testis.|

Research Area: Signal transduction, Metabolism

Synonyms: AMY-1-associating protein expressed in testis 1 , AAT-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year