ABC3H polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.

Research Area: Epigenetics and nuclear signaling, Immunology

Synonyms: DNA dC->dU-editing enzyme APOBEC-3H , EC 3.5.4.-, APOBEC-related protein 10, ARP-10, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year