ABCB6 polyclonal, anti-human

Quantity: 100 µg

Background:
ABCB6, ATP-binding cassette sub-family B member 6, mitochondrialis a protein that in humans is encoded by the ABCB6 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Description:
Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family B member 6, mitochondrial (ABCB6) detection. Tested with WB, IHC-P, ICC in Human.

Synonyms:
ABC antibody, ABC transporter umat antibody, ABC14 antibody, Abcb6 antibody, ABCB6_HUMAN antibody, ATP binding cassette sub family B member 6, mitochondrial precursor antibody, ATP binding cassette, sub family B(MDR/TAP), member 6 antibody, ATP-binding cassette sub-family B member 6 antibody, Mitochondrial ABC transporter 3 antibody, mitochondrial antibody, Mt ABC transporter 3 antibody, Mt-ABC transporter 3 antibody, MTABC3 antibody, P glycoprotein related protein antibody, P-glycoprotein-related protein antibody, PRP antibody, Ubiquitously expressed mammalian ABC half transporter antibody, Ubiquitously-expressed mammalian ABC half transporter antibody, UMAT antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB6(818-842aa YADMWQLQQGQEETSEDTKPQTMER).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.