ABCB6 polyclonal (C-term), anti-human

ABCB6 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP6113a
Catalog Number: AC-AP6113a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1810
Applications: WB, IHC-P
Datasheet

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Background:
The membrane-associated protein ABCB6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Other Names:
ATP-binding cassette sub-family B member 6, mitochondrial, Mitochondrial ABC transporter 3, Mt-ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter, ABCB6, MTABC3, PRP, UMAT

Target/Specificity:
This ABCB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 812-842 amino acids from the C-terminal region of human ABCB6.

Antigen Region:
812-842

Antigen Type: Synthetic Peptide

Gene Name: ABCB6 (HGNC:47)
Gene ID: 10058
Primary Accession: Q9NP58
NCBI Accession: NP_005680.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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