ABCB8 Polyclonal Antibody

Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
ATP binding cassette sub family B member 8, ABCB8, ABCB8, ATP binding cassette sub family B (MDR/TAP) member 8, ATP binding cassette sub family B member 8 mitochondrial, ATP-binding cassette sub-family B member 8, EST328128, M ABC1, M-ABC1, MABC1, Mitochondrial ABC protein, mitochondrial, Mitochondrial ATP binding cassette 1, Mitochondrial ATP-binding cassette 1

Immunogen: Recombinant protein of human ABCB8

Swissprot: Q9NUT2
Gene Accession: BC141836

Calculated MW: 80 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.8 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.