ABCB8 Polyclonal Antibody

Background:
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
ABCB8, EST328128, M-ABC1, MABC1

Immunogen: Recombinant fusion protein of human ABCB8 (NP_009119.2).

Swissprot: Q9NUT2
Gene ID: 11194

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.