ABCC11 polyclonal (N-term), anti-human

ABCC11 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP4787a
Catalog Number: AC-AP4787a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23836
Applications: IHC-P, WB
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Background:
ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.

Other Names:
ATP-binding cassette sub-family C member 11, Multidrug resistance-associated protein 8, ABCC11, MRP8

Target/Specificity:
This ABCC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the N-terminal region of human ABCC11.

Antigen Region:
343-372

Antigen Type: Synthetic Peptide

Gene Name: ABCC11 (HGNC:14639)
Gene ID: 85320
Primary Accession: Q96J66
NCBI Accession: NP_115972.2;NP_149163.2;NP_660187.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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