ABCC8 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release.

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms:
ABC36, Abcc8, ABCC8, ATP binding cassette sub family C (CFTR/MRP) member 8, ATP binding cassette transporter sub family C member 8 (1), ATP-binding cassette sub-family C member 8, HHF1, HI, HRINS, MRP8, PHHI, Sulfonylurea receptor (hyperinsulinemia), Sulfonylurea receptor 1, SUR, SUR1, SUR1delta2, TNDM2

Immunogen: Synthetic peptide of human ABCC8

Swissprot: Q09428
Gene Accession: NP_000343

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:35-1:150

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-5789/sc-5791/sc-25683