ABCE1 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Research Area: Cancer, Metabolism, Immunology, Signal Transduction

Synonyms:
2' 5' oligoadenylate binding protein, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, ABC 38, ABC38, ABCE 1, ABCE1, ABCE1, ATP binding cassette sub family E (OABP) member 1, ATP binding cassette sub family E member 1, ATP-binding cassette sub-family E member 1, HuHP 68, HuHP68, OABP, Ribonuclease 4 inhibitor, Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L inhibitor, RLI, RNase L inhibitor, RNASEL1, RNASELI, RNS 4I, RNS4I

Immunogen: Recombinant protein of human ABCE1

Swissprot: P61221
Gene Accession: BC016283

Calculated MW: 67 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-49337/sc-49338/sc-99064