ABCE1 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Research Area: Cancer, Metabolism, Immunology, Signal Transduction

Synonyms:
ABCE1, ABC38, OABP, RLI, RLI1, RNASEL1, RNASELI, RNS4I

Immunogen: Recombinant fusion protein of human ABCE1 (NP_002931.2).

Swissprot: P61221
Gene ID: 6059

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.