ABCF1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008],function:May function in mRNA translation.,induction:By TNF (in cultured synoviocytes).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. EF3 subfamily.,similarity:Contains 2 ABC transporter domains.,subunit:Interacts with eukaryotic initiation factor 2 (eIF2). Associates with the ribosomes.,tissue specificity:Ubiquitous.,

Synonyms: ABCF1, ABC50, ATP-binding cassette sub-family F member 1, ATP-binding cassette 50, TNF-alpha-stimulated ABC protein

Gene Name: ABCF1

Gene ID: 23

SwissProt ID: Q8NE71

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.