ABCG2 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES4288
Catalog Number: ELK-ES4288
Reactivity: Human
Applications: IF, WB, IHC-p, ELISA
Information
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Reactivity: Human
Applications: IF, WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
ATP binding cassette subfamily G member 2 (Junior blood group)(ABCG2) Homo sapiens The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Names:
ABCG2, ABCP, BCRP, BCRP1, MXR, ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ABCG2. AA range:461-510
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 75
GeneID: ABCG2
Storage: -20°C/1 year
NOTE: For Research Use Only
ATP binding cassette subfamily G member 2 (Junior blood group)(ABCG2) Homo sapiens The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Names:
ABCG2, ABCP, BCRP, BCRP1, MXR, ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ABCG2. AA range:461-510
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 75
GeneID: ABCG2
Storage: -20°C/1 year
NOTE: For Research Use Only
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