ABCG4 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
ABCG4(ATP-Binding Cassette, Subfamily G, Member 4), is a protein that in humans is encoded by the ABCG4 gene. The protein encoded by this gene is included in the superfamily of ATP-binding cassette(ABC) transporters. This protein is a member of the White subfamily and is expressed predominantly in liver tissue. By genomic sequence analysis, Engel et al.(2001) mapped the ABCG4 gene to chromosome 11q23.3. Engel et al.(2001) demonstrated 5-fold induction of ABCG4 following treatment of normal monocyte-derived macrophages with the LXR and RXR agonists 9-cis retinoic acid and 22R hydroxycholesterol. Removal of cholesterol from macrophages by cyclodextrin decreased ABCG4 message levels.

Description:
Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 4 (ABCG4) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
ABCG 4 antibody, ATP binding cassette subfamily G member 4 antibody, ATP-binding cassette, sub-family G(WHITE), member 4 antibody, Putative ABC transporter antibody, WHITE 2 antibody, WHITE2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human ABCG4(327-341aa AVQNGLCAMAEKKSS), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence in the middle region of human ABCG4(327-341aa AVQNGLCAMAEKKSS), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.