ABI2 Polyclonal Antibody

Background:
May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.

Research Area: Cancer

Synonyms:
Abelson interactor 2, ABI 2, Abi-2, ABI2, ABI2, ABI2B, Abl binding protein 3, Abl interacting protein 1 (SH3 containing protein), Abl interactor 2, Abl interactor protein 2b, Abl-binding protein 3, AblBP3, AIP 1, Arg binding protein 1, Arg protein tyrosine kinase binding protein, Arg-binding protein 1, ArgBP1, ARGBPIA, ArgBPIB, OTTHUMP00000163783, OTTHUMP00000163784, OTTHUMP00000206182, OTTHUMP00000206183, OTTHUMP00000206184, OTTHUMP00000206185, SSH3BP2

Immunogen: Fusion protein of human ABI2

Swissprot: Q9NYB9
Gene Accession: BC001439

Calculated MW: 56 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.