ABI3 polyclonal antibody, anti-human, mouse

Background:
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain| proline rich region and Src-homology 3 (SH3) domain| and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and nuclear signaling

Synonyms: ABI gene family member 3 , New molecule including SH3, Nesh

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year