ABI3BP Polyclonal Antibody

Background:
A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

Research Area: Cancer

Synonyms:
ABI gene family member 3 (NESH) binding protein, ABI gene family member 3 binding protein, ABI gene family member 3-binding protein, ABI3BP, FLJ41743, FLJ41754, Nesh binding protein, Nesh BP, Nesh-binding protein, NeshBP, Target of Nesh SH3, Target of Nesh-SH3, Tarsh, TARSH

Immunogen: Recombinant protein of human ABI3BP

Swissprot: Q7Z7G0
Gene Accession: BC030221

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.