ABI3BP Polyclonal Antibody

Background:
A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

Research Area: Cancer

Synonyms:
ABI3BP, NESHBP, TARSH

Immunogen: Recombinant fusion protein of human ABI3BP (NP_056244.2).

Swissprot: Q7Z7G0
Gene ID: 25890

Calculated MW: 53 kDa/72 kDa/86 kDa/118 kDa
Observed MW: 118 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.