ABL2 polyclonal, anti-human, mouse, rat

Protein Family: Protein Kinases

Pathway and Disease: Signal Transduction

Description:
ABL2 (Tyrosine-protein kinase ABL2) regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. ABL2 localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. ABL2 phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

Alternate Names: ABL2, Tyrosine-protein kinase ABL2, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine-protein kinase ARG, ABLL, ARG

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: P42684

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ABL2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.