ABL2 Polyclonal Antibody

Background:
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Research Area: Cancer, Signal Transduction

Synonyms:
Abelson murine leukemia viral oncogene homolog 2, Abelson related gene protein, Abelson tyrosine-protein kinase 2, Abelson-related gene protein, ABL2, ABL2, ABLL, ARG, Tyrosine kinase ARG, Tyrosine protein kinase ABL2, Tyrosine-protein kinase ARG, v abl Abelson murine leukemia viral oncogene homolog 2

Immunogen: Synthetic peptide of human ABL2

Swissprot: P42684
Gene Accession: NP_001129472

Calculated MW: 128 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6356/sc-20708