ACAD11 polyclonal, anti-human, rat
€295.00
In stock
SKU
K008273P
Catalog Number: K008273P
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IHC
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Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IHC
Request Manual
Questions? Contact us!
Background:
The deduced full-length ACAD11 protein contains an N-terminal aminoglycoside phosphotransferase domain, followed by a mitochondria localization signal and ACAD N-terminal, middle, and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variable ACAD11 expression in all tissues examined, with highest expression in adult brain, followed by heart, liver, spinal cord, and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11 associated with mitochondrial membranes, but not mitochondrial matrix. Immunohistochemical analysis showed that ACAD11colocalized with a mitochondrial marker in human neuroblastoma cells.
Synonyms: ACAD-11
Cellular Location: Cytoplasm
Immunogen:
Recombinant protein of human ACAD11
Gene Symbol: ACAD11
Gene ID: 84129
Swiss prot: Q709F0
Calculated MW: 87kDa
Recommended dilution:
WB 1:200-1000, IHC 1:15-50,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
The deduced full-length ACAD11 protein contains an N-terminal aminoglycoside phosphotransferase domain, followed by a mitochondria localization signal and ACAD N-terminal, middle, and C-terminal domains. It also has a glycosylation site and a C-terminal peroxisome-targeting signal. The ACAD domain contains a catalytic aspartate rather than the catalytic glutamate found in most other ACADs. Real-time RT-PCR detected variable ACAD11 expression in all tissues examined, with highest expression in adult brain, followed by heart, liver, spinal cord, and kidney. Western blot analysis of fractionated human cerebellum and kidney revealed thatACAD11 associated with mitochondrial membranes, but not mitochondrial matrix. Immunohistochemical analysis showed that ACAD11colocalized with a mitochondrial marker in human neuroblastoma cells.
Synonyms: ACAD-11
Cellular Location: Cytoplasm
Immunogen:
Recombinant protein of human ACAD11
Gene Symbol: ACAD11
Gene ID: 84129
Swiss prot: Q709F0
Calculated MW: 87kDa
Recommended dilution:
WB 1:200-1000, IHC 1:15-50,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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