ACCN1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.

Synonyms: ASIC2,ACCN,ASIC2a,BNC1,BNaC1,MDEG,hBNaC1,acid-sensing ion channel 2

Cellular Location: Cell membrane

Immunogen:
A synthetic peptide of human ACCN1

Gene Symbol: ACCN1

Gene ID: 40

Swiss prot: Q16515

Calculated MW: 58/63kDa

Recommended dilution:
WB 1:5000-8000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.