ACCN3 polyclonal (N-term), anti-human

ACCN3 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP19124a
Catalog Number: AC-AP19124a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40995
Applications: WB
Datasheet

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Background:
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms.

Other Names:
Acid-sensing ion channel 3, ASIC3, hASIC3, Amiloride-sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, Testis sodium channel 1, hTNaC1, ASIC3, ACCN3, SLNAC1, TNAC1

Target/Specificity:
This ACCN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ACCN3.

Antigen Region:
55-83

Antigen Type: Synthetic Peptide

Gene Name: ASIC3
Gene ID: 9311
Primary Accession: Q9UHC3
NCBI Accession: NP_004760.1;NP_064717.1;NP_064718.1
Other Accession: NP_064718.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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