ACD Polyclonal Antibody

Background:
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
Acd, ACD, Adrenocortical dysplasia homolog, Adrenocortical dysplasia protein homolog, PIP1, POT1 and TIN2 organizing protein, POT1 and TIN2-interacting protein, TIN2 interacting protein 1, TINT1, TPP1

Immunogen: Synthetic peptide of human ACD

Swissprot: Q96AP0
Gene Accession: NP001075955

Calculated MW: 58 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.