ACE antibody (clone 6A4), anti-human
€435.00
In stock
SKU
AC-AT1024a
Catalog Number: AC-AT1024a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, E
Request Information AC-AT1024a">Request Information
Background:
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.
Other Names:
Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1
Antigen Type:
Recombinant Protein
Gene Name: ACE {ECO:0000303|PubMed:2849100, ECO:0000312|HGNC:HGNC:2707}
Gene ID: 1636
NCBI Accession: NP_000780.1;NP_001171528.1;NP_690043.1
Primary Accession: P12821
Other Accession: BC036375
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.
Other Names:
Angiotensin-converting enzyme, ACE, 321-, Dipeptidyl carboxypeptidase I, Kininase II, CD143, Angiotensin-converting enzyme, soluble form, ACE, DCP, DCP1
Antigen Type:
Recombinant Protein
Gene Name: ACE {ECO:0000303|PubMed:2849100, ECO:0000312|HGNC:HGNC:2707}
Gene ID: 1636
NCBI Accession: NP_000780.1;NP_001171528.1;NP_690043.1
Primary Accession: P12821
Other Accession: BC036375
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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