ACE polyclonal, anti-human, mouse, rat

Background:
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Synonyms: ACE1, CD143, DCP, DCP1

Cellular Location: Cell membrane Cytoplasm Secreted Single-pass type I membrane protein

Immunogen:
A synthetic peptide of human ACE

Gene Symbol: ACE

Gene ID: 1636

Swiss prot: P12821

Calculated MW: 150kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.