Acetyl-Histone H3-K14 polyclonal, anti-human, mouse, rat

Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Synonyms: H3.4, H3/g, H3FT, H3t

Cellular Location: Chromosome Nucleus

Immunogen:
A synthetic acetylated peptide corresponding to residues surrounding K14 of human H3

Gene Symbol: Acetyl-Histone H3-K14

Gene ID: 8290

Swiss prot: Q16695

Calculated MW: 16kDa

Recommended dilution:
WB 1:1000-3000, IHC 1:200-500, IF 1:500-1000, IP 1:200-500, ChIP 1:50-100, ChIPseq 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.