Acetyl-Histone H3 (Lys9) Polyclonal Antibody

Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3

Immunogen: Synthesized peptide derived from human Histone H3 around the acetylation site of K9

Swissprot: P68431,Q71DI3,P84243

Calculated MW: 15 kDa
Observed MW: 17 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.