ACF polyclonal (C-term), anti-human

Background:
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events.

Other Names:
APOBEC1 complementation factor, APOBEC1-stimulating protein, A1CF, ACF, ASP {ECO:0000312|EMBL:CAB947541}

Target/Specificity:
This ACF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human ACF.

Antigen Region:
394-423

Antigen Type: Synthetic Peptide

Gene Name: A1CF
Gene ID: 29974
Primary Accession: Q9NQ94
NCBI Accession: NP_001185747.1;NP_001185748.1;NP_001185749.1;NP_055391.2;NP_620310.1;NP_620311.1
Other Accession: NP_620310
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.