AChE polyclonal antibody, anti-human, mouse, rat

Background:
Acetylcholinesterase hydrolyzes the neurotransmitter| acetylcholine at neuromuscular junctions and brain cholinergic synapses| and thus terminates signal transmission. It is also found on the red blood cell membranes| where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties| but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene| and the structural diversity in the gene products arises from alternative mRNA splicing| and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain| muscle and other tissues is the hydrophilic species| which forms disulfide-linked oligomers with collagenous| or lipid-containing structural subunits. The other| alternatively

Research Area: Cardiovascular, Neuroscience, Cancer, Immunology, Metabolism

Synonyms: Acetylcholinesterase, ACHE, Acetylcholinesterase, AChE

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year