AChRα3 Polyclonal Antibody

Background:
cholinergic receptor nicotinic alpha 3 subunit(CHRNA3) Homo sapiens This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009],

Alternative Names:
CHRNA3, NACHRA3, Neuronal acetylcholine receptor subunit alpha-3

Immunogen: The antiserum was produced against synthesized peptide derived from human AChRalpha3. AA range:90-139

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 57

GeneID: CHRNA3

Storage: -20°C/1 year

NOTE: For Research Use Only