Acidic Hair Keratin K31 (hHa1) polyclonal, anti-human, mouse

Quantity: 25 µl

Background:
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.

Synonyms:
KRT31, HA1, Ha-1, hHa1, KRTHA1

Isotype: Guinea pig Polyclonal (GP-hHa1)

Immunogen:
Complete recombinant human hair (trichocytic) keratin K31 (formerly also designated keratin hHa1), coupled to KLH

Form: Stabilized Serum

Specificity:
The antiserum stains specifically human hair keratin K31 expressed starting from the lower hair cortex.

Reactivity: human, mouse

Applications: Immunohistochemistry on frozen sections, Immunoblotting (western, ECL)

Working DIlution: 1:200 for immunohistochemistry; 1:2000 for Immunoblotting

Storage: 2-8C

References:
- Jave-Suarez LF. et al. (2004) J Invest Dermatol 122: 555-564
- Langbein L. (2004) Methods in Cell Biology 78: 413-456