ACK-1 polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Folding, Sorting and Degradation, Signaling Molecules and Interaction

Description:
ACK-1 (Activated CDC42 kinase 1) is a tyrosine kinase which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. ACK-1 binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR. ACK-1 also participates in clathrin-mediated endocytosis.

Alternate Names: ACK-1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2, TNK2, ACK1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q07912

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ACK-1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.