ACKR2 polyclonal, anti-human

Background:
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Synonyms: D6, hD6, CCR9, CCBP2, CCR10, CMKBR9

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human ACKR2

Gene Symbol: ACKR2

Gene ID: 1238

Swiss prot: O00590

Calculated MW: 43kDa

Recommended dilution:
WB 1:200-1000, IHC 1:30-150,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.