ACMSD Antibody (N-term) Blocking Peptide

ACMSD Antibody (N-term) Blocking Peptide

€363.00
In stock
SKU
AC-BP8954a
Catalog Number: AC-BP8954a
Size: 500 µg
Datasheet
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Background:
ACMSD is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS).ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Other Names:
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, Picolinate carboxylase, ACMSD

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8954a was selected from the N-term region of human ACMSD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: ACMSD

Gene ID: 130013
Primary Accession: Q8TDX5
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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