ACMSD polyclonal, anti-human, mouse

Background:
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Synonyms: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, Picolinate carboxylase

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human ACMSD

Gene Symbol: ACMSD

Gene ID: 130013

Swiss prot: Q8TDX5

Calculated MW: 38kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.